About

The Centre for the Analysis of Genome Evolution and Function (CAGEF) is an extra-departmental unit established through generous funding by the University of Toronto’s Academic Initiative Fund in 2006 in order to promote interdisciplinary research  in comparative, evolutionary, and functional analyses of genomes and proteomes. CAGEF’s mission is to promote research in basic and applied genome biology research, provide technical support and access to state-of-art genomic, proteomic, metabolomic, chemical genomic, and bioinformatic research platforms, and to promote the training and education of students and postdocs through the development and support of innovative teaching initiatives, courses, workshops and research awards.

CAGEF is closely allied with the departments of Cell and Systems Biology and Ecology and Evolutionary Biology at the University of Toronto, and a proud supporter and sponsor of the Collaborative Graduate Program in Genome Biology and Bioinformatics

 

CAGEF DEVELOPED PROTOCOLS

Next Generation Mapping

Next Generation Mapping harnesses the power of Next Generation Sequencing technology to efficiently map point mutations, identifying the causative lesion of phenotypically identifiable mutations. Austin et al., 2011

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Quantitative Interactor Screen Sequencing

Quantitative Interactor Screen Sequencing applies next generation sequencing to yeast two-hybrid interaction screens to quantitatively measure enrichment of candidate interactors. Lewis et al., 2012

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