Publications

CAGEF has contributed to over 360 publications.

Triphosphate Tunnel Metalloenzyme Function in Senescence Highlights a Biological Diversification of This Protein Superfamily

Posted by on Dec 5, 2017 in Publications | Comments Off on Triphosphate Tunnel Metalloenzyme Function in Senescence Highlights a Biological Diversification of This Protein Superfamily

Ung H, Karia P, Ebine K, Ueda T, Yoshioka K, Moeder W Plant Physiol. 2017 Sep;175(1):473-485 PMID: 28733390
Abstract: The triphosphate tunnel metalloenzyme (TTM) superfamily comprises a group of enzymes that hydrolyze organophosphate substrates. They exist in all domains of life, yet the biological role of most family members is unclear. Arabidopsis (Arabidopsis thaliana) encodes three TTM genes. We have previously reported that AtTTM2 displays pyrophosphatase activity and is involved in pathogen resistance. Here, we report the biochemical...

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A high-sensitivity, microtiter-based plate assay for plant MAMP-triggered immunity

Posted by on Dec 5, 2017 in Publications | Comments Off on A high-sensitivity, microtiter-based plate assay for plant MAMP-triggered immunity

Mott GA, Desveaux D, Guttman DS Mol. Plant Microbe Interact. 2017 Dec; PMID: 29199888
Abstract: The first step in the plant immune response to pathogen challenge involves the perception of conserved epitopes, called microbe-associated molecular patterns (MAMPs), by cell surface pattern recognition receptors (PRRs). Given the key roles that MAMPs and PRRs play in plant innate immunity, great effort has been expended to identify these molecules. Current methods for assaying these immune responses are often limited in their resolution and...

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Oh, the places they’ll go! A survey of phytopathogen effectors and their host targets

Posted by on Dec 5, 2017 in Publications | Comments Off on Oh, the places they’ll go! A survey of phytopathogen effectors and their host targets

Khan M, Seto D, Subramaniam R, Desveaux D Plant J. 2017 Nov; PMID: 29160935
Abstract: Phytopathogens translocate effector proteins into plant cells where they sabotage the host cellular machinery to promote infection. An individual pathogen can translocate numerous distinct effectors during the infection process to target an array of host macromolecules (proteins, metabolites, DNA, etc…) and manipulate them using a variety of enzymatic activities. In this review, we have surveyed the literature for effector targets and curated them to convey...

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Identification and analysis of seven effector protein families with different adaptive and evolutionary histories in plant-associated members of the Xanthomonadaceae

Posted by on Dec 4, 2017 in Publications | Comments Off on Identification and analysis of seven effector protein families with different adaptive and evolutionary histories in plant-associated members of the Xanthomonadaceae

Assis RAB, Polloni LC, Patané JSL, Thakur S, Felestrino ÉB, Diaz-Caballero J, Digiampietri LA, Goulart LR, Almeida NF, Nascimento R, Dandekar AM, Zaini PA, Setubal JC, Guttman DS, Moreira LM Sci Rep. Published Nov 23, 2017. https://doi.org/10.1038/s41598-017-16325-1 PMID: 29170530
Abstract: The Xanthomonadaceae family consists of species of non-pathogenic and pathogenic γ-proteobacteria that infect different hosts, including humans and plants. In this study, we performed a comparative analysis using 69 fully sequenced genomes belonging to...

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Convergent selection pressures drive the evolution of rhodopsin kinetics at high altitudes via non-parallel mechanisms

Posted by on Dec 4, 2017 in Publications | Comments Off on Convergent selection pressures drive the evolution of rhodopsin kinetics at high altitudes via non-parallel mechanisms

Castiglione GM, Schott RK, Hauser FE, Chang BSW Evolution. Published Nov 16, 2017. https://doi.org/10.1111/evo.13396 PMID: 29143302
Abstract: Convergent evolution in response to similar selective pressures is a well-known phenomenon in evolutionary biology. Less well understood is how selection drives convergence in protein function, and the underlying mechanisms by which this can be achieved. Here we investigate functional convergence in the visual system of two distantly related lineages of high-altitude adapted Andean and Himalayan...

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Insights into visual pigment adaptation and diversity from model ecological and evolutionary systems

Posted by on Dec 4, 2017 in Publications | Comments Off on Insights into visual pigment adaptation and diversity from model ecological and evolutionary systems

Hauser FE, Chang BS Curr Opin Genet Dev. Published Nov 2, 2017. https://doi.org/10.1016/j.gde.2017.09.005 PMID: 29102895
Abstract: Sensory systems provide valuable insight into the evolution of molecular mechanisms underlying organismal anatomy, physiology, and behaviour. Visual pigments, which mediate the first step in visual transduction, offer a unique window into the relationship between molecular variation and visual performance, and enhance our understanding of how ecology, life history, and physiology may shape genetic variation across a...

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Staphylococcus aureus interaction with Pseudomonas aeruginosa biofilm enhances tobramycin resistance

Posted by on Dec 4, 2017 in Publications | Comments Off on Staphylococcus aureus interaction with Pseudomonas aeruginosa biofilm enhances tobramycin resistance

Beaudoin T, Yau YCW, Stapleton PJ, Gong Y, Wang PW, Guttman DS, Waters V NPJ Biofilms Microbiomes. Published Oct 19, 2017. https://doi.org/DOI PMID: 29062489
Abstract: Antimicrobial resistance is a significant threat to the treatment of infectious disease. Multiple mechanisms of resistance to different classes of antibiotics have been identified and well-studied. However, these mechanisms are studied with bacteria in isolation, whereas often, infections have a polymicrobial basis. Using a biofilm slide chamber model, we visualized the formation...

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Exocyst, exosomes, and autophagy in the regulation of Brassicaceae pollen-stigma interactions

Posted by on Dec 4, 2017 in Publications | Comments Off on Exocyst, exosomes, and autophagy in the regulation of Brassicaceae pollen-stigma interactions

Goring DR J Exp Bot. Published Sep 27, 2017. https://doi.org/10.1093/jxb/erx340 PMID: 29036428
Abstract: Brassicaceae pollen-stigma interactions have been extensively studied in Brassica and Arabidopsis species to identify cellular events triggered in the stigmatic papillae by pollen contact. Compatible pollinations are linked to the activation of basal cellular responses in the stigmatic papillae, which include calcium gradients, actin networks, and polarized secretion. The occurrence of these cellular events in stigmatic papillae coincides...

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Cesarean Section, Formula Feeding, and Infant Antibiotic Exposure: Separate and Combined Impacts on Gut Microbial Changes in Later Infancy

Posted by on Dec 4, 2017 in Publications | Comments Off on Cesarean Section, Formula Feeding, and Infant Antibiotic Exposure: Separate and Combined Impacts on Gut Microbial Changes in Later Infancy

Yasmin F, Tun HM, Konya TB, Guttman DS, Chari RS, Field CJ, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Sears MR; CHILD Study Investigators, Scott JA, Dinu I, Kozyrskyj AL Front Pediatr. Published Sep 26, 2017. https://doi.org/10.3389/fped.2017.00200 PMID: 29018787
Abstract: Established during infancy, our complex gut microbial community is shaped by medical interventions and societal preferences, such as cesarean section, formula feeding, and antibiotic use. We undertook this study to apply the significance analysis of microarrays (SAM)...

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Accelerated Evolution and Functional Divergence of the Dim Light Visual Pigment Accompanies Cichlid Colonization of Central America

Posted by on Dec 4, 2017 in Publications | Comments Off on Accelerated Evolution and Functional Divergence of the Dim Light Visual Pigment Accompanies Cichlid Colonization of Central America

Hauser FE, Ilves KL, Schott RK, Castiglione GM, López-Fernández H, Chang BSW Mol Biol Evol. Published Oct 1, 2017. https://doi.org/10.1093/molbev/msx192 PMID: 28957507
Abstract: Cichlids encompass one of the most diverse groups of fishes in South and Central America, and show extensive variation in life history, morphology, and colouration. While studies of visual system evolution in cichlids have focussed largely on the African rift lake species flocks, Neotropical cichlids offer a unique opportunity to investigate visual system evolution at...

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